Dichloromethane → 4-(Azetidin-3-yl)piperazin-2-one

HRID 1237991

Reaction equation

HRID 1237991 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH:10]([N:12]2[CH2:13][C:14](=[O:18])[NH:15][CH2:16][CH2:17]2)[CH2:11]1)([CH3:5])([CH3:6])[CH3:7].[Cl:26][CH2:27][Cl:28].[F:19][C:20]([F:21])([F:22])[C:23]([OH:24])=[O:25]>>[NH:8]1[CH2:9][CH:10]([N:12]2[CH2:13][C:14](=[O:18])[NH:15][CH2:16][CH2:17]2)[CH2:11]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 596054391-Boc-3-(3-oxo-1-piperazinyl)azetidine

Product 1

HCID 596061454-(Azetidin-3-yl)piperazin-2-one

Sources & evidence

ORD record
ord-f5a645ac6afe4abb9c8bcae51b39a1a0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Linked notes

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