Hydrochloric Acid → HCID 12282158, compound
Reaction equation
[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][CH:3]=1.[CH2:10]([O:12]CC)[CH3:11].Cl>C(O)C>[ClH:1].[CH2:10]([O:12][C:6](=[NH:7])[C:5]1[CH:8]=[CH:9][C:2]([Cl:1])=[CH:3][CH:4]=1)[CH3:11]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
10 g of 4-chlorobenzonitrile was suspended in 12 ml of ethanol and dissolved by adding diethyl ether. While being cooled in an ice bath, it was saturated with HCl gas. After 72 hours, precipitated product was suctioned out. The product was washed with diethyl ether.
Workup
- dissolutiondissolved
- temperatureWhile being cooled in an ice bath
- customprecipitated product
- washThe product was washed with diethyl ether
Sources & evidence
- ORD record
- ord-e645725a5d734b9fb8466411bedaa264
- Source dataset
- uspto-grants-2006_10
- Patent number
- US07115645B2
Reaction notes
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