Methanol → 17-Ethyl-1,2,14-trihydroxy-12-[2'-(4"-(naphth-2-yl)-3"-methoxycyclohexyl)-1'-methylvinyl]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-3,10,16-trione

HRID 124462

Reaction equation

HRID 124462 reaction equation
[CH2:6]([CH3:7])[CH:8]1[C:9](=[O:70])[CH2:10][CH:11]([OH:69])[CH:12]([CH3:68])[CH:13]([C:47](=[CH:48][CH:49]2[CH2:50][CH:51]([O:65][CH3:66])[CH:52]([c:55]3[cH:56][c:57]4[cH:58][cH:59][cH:60][cH:61][c:62]4[cH:63][cH:64]3)[CH2:53][CH2:54]2)[CH3:67])[O:14][C:15](=[O:46])[CH:16]2[CH2:17][CH2:18][CH2:19][CH2:20][N:21]2[C:22](=[O:45])[C:23](=[O:44])[C:24]2([OH:43])[CH:25]([CH3:42])[CH2:26][CH:27]([O:40][CH3:41])[CH:28]([CH:29]([O:37][CH3:38])[CH2:30][CH:31]([CH3:36])[CH2:32][C:33]([CH3:35])=[CH:34]1)[O:39]2.[CH2:71]1[O:72][CH2:73][CH2:74][CH2:75]1.[CH2:78]1[O:79][CH2:80][CH2:81][CH2:82]1.[CH3:76][OH:77].[I:1][CH2:2][CH2:3][I:4].[Sm:5]>>[CH2:6]([CH3:7])[CH:8]1[C:9](=[O:70])[CH2:10][CH:11]([OH:69])[CH:12]([CH3:68])[CH:13]([C:47](=[CH:48][CH:49]2[CH2:50][CH:51]([O:65][CH3:66])[CH:52]([c:55]3[cH:56][c:57]4[cH:58][cH:59][cH:60][cH:61][c:62]4[cH:63][cH:64]3)[CH2:53][CH2:54]2)[CH3:67])[O:14][C:15](=[O:46])[CH:16]2[CH2:17][CH2:18][CH2:19][CH2:20][N:21]2[C:22](=[O:45])[CH:23]([OH:44])[C:24]2([OH:43])[CH:25]([CH3:42])[CH2:26][CH:27]([O:40][CH3:41])[CH:28]([CH:29]([O:37][CH3:38])[CH2:30][CH:31]([CH3:36])[CH2:32][C:33]([CH3:35])=[CH:34]1)[O:39]2

Participants

6

Reactant 5

HCID 887MethanolHCID 8028Tetrahydrofuran2×HCID 122241,2-DiiodoethaneHCID 23951SamariumHCID 5718413317-Ethyl-1,14-dihydroxy-12-[2'-(4"-(naphth-2-yl)-3"-methoxycyclohexyl)-1'-methylvinyl]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetraone

Product 1

HCID 5712063717-Ethyl-1,2,14-trihydroxy-12-[2'-(4"-(naphth-2-yl)-3"-methoxycyclohexyl)-1'-methylvinyl]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-3,10,16-trione

Sources & evidence

ORD record
ord-ce88a3f23fb94279a1f40d5a69857b42
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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