Ethanol → HCID 69639835, compound

HRID 1246586

Reaction equation

HRID 1246586 reaction equation
[Na].C(O)C.[NH2:5][C:6]1[CH:16]=[CH:15][C:9]([C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:8][CH:7]=1.[CH3:17][CH:18]([CH2:22][C:23]([CH3:26])([CH3:25])[CH3:24])CCO>C1CCCCC1>[NH2:5][C:6]1[CH:7]=[CH:8][C:9]([C:10]([O:12][CH2:13][CH2:14][CH:18]([CH3:17])[CH2:22][C:23]([CH3:26])([CH3:25])[CH3:24])=[O:11])=[CH:15][CH:16]=1

Participants

6

Reactant 4

HCID 702Ethanol2×HCID 2337BenzocaineHCID 189383,5,5-Trimethyl-1-hexanolHCID 5360545Sodium

Product 1

HCID 69639835HCID 69639835, compound

Reagents, catalysts & solvents 1

HCID 8078CyclohexaneSolvent

Procedure

Sodium metal (1 g cat.) was added to ethanol (30 mL) to give a solution which was added to a suspension of ethyl 4-aminobenzoate (175 g, 1.06 mol) and 3,5,5 trimethyl hexanol (200 g, 1.4 mol) in cyclohexane (300 mL). The suspension was heated under reflux for 24 hours with the azeotropic removal of ethanol.

Workup

  1. customto give a solution which
  2. temperatureThe suspension was heated

Sources & evidence

ORD record
ord-74ff96502e7f4c339282b0b43bcc57c1
Source dataset
uspto-grants-2006_10
Patent number
US07129204B2

Linked notes

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