Carbon Disulfide → HCID 178524147, compound
Reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[NH2:11])[C:5]([OH:7])=[O:6].[C:12](=S)=[S:13].C(N(CC)CC)C>O1CCOCC1>[SH:13][C:12]1[NH:1][C:2]2[CH:3]=[C:4]([C:5]([OH:7])=[O:6])[CH:8]=[CH:9][C:10]=2[N:11]=1Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
30.4 g of 3,4-diaminobenzoic acid, 50 g of carbon disulfide and 50 g of triethylamine were dissolved in 200 ml of dioxane and the solution was refluxed by heating for 5 hours. The reaction mixture was cooled to room temperature, the crystals thus deposited were collected by filtration and recrystallized from water to obtain 14 g of 2-mercapto-5-carboxybenzimidazole. Melting Point: above 250° C.
Workup
- temperaturethe solution was refluxed
- temperatureby heating for 5 hours
- filtrationthe crystals thus deposited were collected by filtration
- customrecrystallized from water
Sources & evidence
- ORD record
- ord-7d5bf081ce334ceb8deaaefec3a6d7b0
- Source dataset
- uspto-grants-1986_12
- Patent number
- US04628024
Reaction notes
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