D-Arabitol → D-Xylulose

HRID 1250810

Reaction equation

HRID 1250810 reaction equation
[O:1]=[CH:2][C@@H:3]([C@H:5]([C@@H:7]([C@@H:9](CO)[OH:10])[OH:8])[OH:6])[OH:4].[CH2:13]([OH:22])[C@@H:14]([OH:21])[CH:15]([OH:20])[C@H:16]([OH:19])[CH2:17][OH:18]>C(O)C>[OH:1][CH2:2][C:3]([C@H:5]([C@@H:7]([CH2:9][OH:10])[OH:8])[OH:6])=[O:4].[CH2:17]([OH:18])[C@@H:16]([C@H:15]([C@@H:14]([CH2:13][OH:22])[OH:21])[OH:20])[OH:19]

Participants

5

Reactant 2

HCID 94154D-ArabitolHCID 107526(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal

Product 2

HCID 5289590D-XyluloseHCID 178418489HCID 178418489, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Based on this idea, as shown in Example 6, glucose and ethanol were added and allowed to react in a conversion reaction of D-arabitol using Gluconobacter oxydans ATCC621 and the effect of their addition was examined. As a result, a considerable effect of addition was recognized as shown in Example 6. That is, when no carbon source was added, a portion of D-xylulose remained unreacted, giving a low yield of xylitol whereas with the addition of a carbon source, reduction of D-xylulose to xylitol proceeded advantageously and the yield of xylitol (based on the yield of D-arabitol) reached at most 98%.

Workup

  1. additionwere added
  2. additionthe effect of their addition
  3. additionAs a result, a considerable effect of addition
  4. additionwhen no carbon source was added

Sources & evidence

ORD record
ord-73267700da3b46d6b36fb68f5da2280f
Source dataset
uspto-grants-2002_01
Patent number
US06340582B1

Linked notes

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