Ethyl 5-aminocarbonyl-4,6-dimethoxy-2-(trifluoromethyl)-3-pyridinecarboxylate → HCID 13726807, compound
Reaction equation
[NH2:1][C:2]([C:4]1[C:5]([O:21][CH3:22])=[C:6]([C:16]([O:18][CH2:19][CH3:20])=[O:17])[C:7]([C:12]([F:15])([F:14])[F:13])=[N:8][C:9]=1[O:10][CH3:11])=O>O=P(Cl)(Cl)Cl>[C:2]([C:4]1[C:5]([O:21][CH3:22])=[C:6]([C:16]([O:18][CH2:19][CH3:20])=[O:17])[C:7]([C:12]([F:15])([F:13])[F:14])=[N:8][C:9]=1[O:10][CH3:11])#[N:1]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
This material was obtained in 84.9% yield from the product of Example 22 (0.014 mol) and 100 ml of POCl3 by a procedure similar to that in Example 24 as a solid: mp 32°-34° C.
Sources & evidence
- ORD record
- ord-c6bbd967797049f6a07f11533972bd44
- Source dataset
- uspto-grants-1988_05
- Patent number
- US04741766
Reaction notes
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