1,2-Dichloroethane → 1-((2-Chloro-4-morpholinothieno[2,3-d]pyrimidin-6-yl)methyl)pyrrolidin-3-ol

HRID 125784

Reaction equation

HRID 125784 reaction equation
[C:25]([OH:26])(=[O:27])[CH3:28].[Cl:1][c:2]1[n:3][c:4]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:5]2[c:6]([n:7]1)[s:8][c:9]([CH:11]=[O:12])[cH:10]2.[Cl:29][CH2:30][CH2:31][Cl:32].[NH:19]1[CH2:20][CH:21]([OH:24])[CH2:22][CH2:23]1>>[Cl:1][c:2]1[n:3][c:4]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:5]2[c:6]([n:7]1)[s:8][c:9]([CH2:11][N:19]1[CH2:20][CH:21]([OH:24])[CH2:22][CH2:23]1)[cH:10]2

Participants

5

Reactant 4

HCID 111,2-DichloroethaneHCID 176Acetic AcidHCID 982104-HydroxypyrrolidineHCID 568338442-Chloro-4-morpholinothieno[2,3-d]pyrimidine-6-carbaldehyde

Product 1

HCID 582339241-((2-Chloro-4-morpholinothieno[2,3-d]pyrimidin-6-yl)methyl)pyrrolidin-3-ol

Sources & evidence

ORD record
ord-76964ed44318416a9f0c6ec48b2a677e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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