2-(p-Nonylphenoxy)ethanol → Tergitol mesylate

HRID 1260124

Reaction equation

HRID 1260124 reaction equation
C(N(CC)CC)C.[CH3:8][CH2:9][CH2:10][CH2:11][CH:12]([CH2:15][CH2:16][CH:17]([O:22][S:23]([O-:26])(=[O:25])=[O:24])[CH2:18][CH:19]([CH3:21])[CH3:20])[CH2:13][CH3:14].[Na+:27].[CH3:28]CCCCCCCCC1C=CC(OCCO)=CC=1>C(Cl)Cl>[CH3:8][CH2:9][CH2:10][CH2:11][CH:12]([CH2:15][CH2:16][CH:17]([O:22][S:23]([O-:26])(=[O:25])=[O:24])[CH2:18][CH:19]([CH3:20])[CH3:21])[CH2:13][CH3:14].[Na+:27].[S:23]([O-:26])(=[O:24])(=[O:22])[CH3:28]

Participants

5

Reactant 3

HCID 77002-(p-Nonylphenoxy)ethanolHCID 8471TriethylamineHCID 23665772Sodium Tetradecyl Sulfate

Product 1

HCID 131730653Tergitol mesylate

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The Tergitol-mesylate was synthesized as depicted in Reaction Scheme 3 and FIG. 1. In step S1, 4.86 g (48 mmol) of triethylamine (Aldrich) was added to a solution of Tergitol®NP-9 (16 mmol, Aldrich) in anhydrous methylene chloride (20 ml) in a reactor. The mixture was stirred under a nitrogen atmosphere for 10 minutes.

Workup

  1. customas depicted in Reaction Scheme 3 and FIG. 1

Sources & evidence

ORD record
ord-dad952767dde4a789f995cfa6f92a9cc
Source dataset
uspto-grants-2013_06
Patent number
US08470209B2

Linked notes

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