Acetonitrile → 2-(2-Bromophenyl)-6-chloro-4,4-dimethyl-1,2,3,4-tetrahydroquinoline

HRID 126050

Reaction equation

HRID 126050 reaction equation
[Br:9][c:10]1[c:11]([CH:12]=[O:13])[cH:14][cH:15][cH:16][cH:17]1.[CH2:18]=[C:19]([CH3:20])[CH3:21].[CH3:47][C:48]#[N:49].[CH3:50][CH2:51][O:52][C:53](=[O:54])[CH3:55].[Cl:1][c:2]1[cH:3][cH:4][c:5]([NH2:8])[cH:6][cH:7]1.[F:22][C:23]([F:24])([F:25])[S:26]([O-:27])(=[O:28])=[O:29].[F:31][C:32]([F:33])([F:34])[S:35]([O-:36])(=[O:37])=[O:38].[F:39][C:40]([F:41])([F:42])[S:43]([O-:44])(=[O:45])=[O:46].[Yb+3:30]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:7]1)[C:19]([CH3:20])([CH3:21])[CH2:18][CH:12]([c:11]1[c:10]([Br:9])[cH:17][cH:16][cH:15][cH:14]1)[NH:8]2

Participants

8

Reactant 7

HCID 6342AcetonitrileHCID 78124-ChloroanilineHCID 8255IsobutyleneHCID 8857Ethyl AcetateHCID 811292-BromobenzaldehydeHCID 105055Ytterbium(3+)HCID 2758875Trifluoromethanesulfonate3×

Product 1

HCID 672903632-(2-Bromophenyl)-6-chloro-4,4-dimethyl-1,2,3,4-tetrahydroquinoline

Sources & evidence

ORD record
ord-30e06ef81fae4ac3970c42c7f8e009ee
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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