Acetic Acid → Tert-butyl 3-(4-bromophenyl)-3-hydroxyazetidine-1-carboxylate

Reaction equation

[Br-:23].[CH3:25][OH:26].[CH3:35][C:36](=[O:37])[OH:38].[Cl:27][N:28]1[C:29](=[O:30])[CH2:31][CH2:32][C:33]1=[O:34].[K+:24].[OH:1][C:2]1([c:13]2[cH:14][cH:15][c:16]([Si:19]([CH3:20])([CH3:21])[CH3:22])[cH:17][cH:18]2)[CH2:3][N:4]([C:6](=[O:7])[O:8][C:9]([CH3:10])([CH3:11])[CH3:12])[CH2:5]1>>[OH:1][C:2]1([c:13]2[cH:14][cH:15][c:16]([Br:23])[cH:17][cH:18]2)[CH2:3][N:4]([C:6](=[O:7])[O:8][C:9]([CH3:10])([CH3:11])[CH3:12])[CH2:5]1

Participants

Reactant 6

HCID 176Acetic Acid

HCID 259Bromide ion

HCID 813Potassium Cation

HCID 887Methanol

HCID 31398Chlorosuccinimide

HCID 58079820HCID 58079820, compound

Product 1

HCID 58079783Tert-butyl 3-(4-bromophenyl)-3-hydroxyazetidine-1-carboxylate

Sources & evidence

ORD record: ord-75da00d65bef4990a85b4dcd453eb043
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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