Ethylamine → 2,2-Diphenyl-N-ethylacetamide

Reaction equation

[C:1]1([CH:7]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:8](Cl)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:17]([NH2:19])[CH3:18]>>[CH2:17]([NH:19][C:8](=[O:9])[CH:7]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)[CH3:18]

Participants

Reactant 2

HCID 6341Ethylamine

HCID 746372,2-Diphenylacetyl chloride

Product 1

HCID 2570312,2-Diphenyl-N-ethylacetamide

Procedure

The title compound, off-white solid, m.p. 87° C. and MS: m/e=239 (M+) was prepared in accordance with the general method of example 1 from diphenylacetyl chloride and ethylamine.

Sources & evidence

ORD record: ord-fb1380761ef74049a0e26ece55eb0275
Source dataset: uspto-grants-2003_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06548522B1

Reaction notes

Loading…