3,5-Dichloroaniline → Benzeneacetic acid, 2-[(3,5-dichlorophenyl)amino]-

Reaction equation

Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[Cl:12][C:13]1[CH:14]=[C:15]([CH:17]=[C:18]([Cl:20])[CH:19]=1)[NH2:16]>>[Cl:12][C:13]1[CH:14]=[C:15]([NH:16][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[CH2:8][C:9]([OH:11])=[O:10])[CH:17]=[C:18]([Cl:20])[CH:19]=1

Participants

Reactant 2

HCID 122813,5-Dichloroaniline

HCID 877542-Bromophenylacetic acid

Product 1

HCID 10469807Benzeneacetic acid, 2-[(3,5-dichlorophenyl)amino]-

Procedure

In the manner described in example 3, 2-bromophenylacetic acid was condensed with 3,5-dichloroaniline to yield 2-[(3,5-dichlorophenyl)amino]phenylacetic acid.

Sources & evidence

ORD record: ord-03fa153da4cd48f0b2336d42fc3673a9
Source dataset: uspto-grants-2003_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06552077B2

Reaction notes

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