P-Cresol → 1-Methyl-4-(prop-2-yn-1-yloxy)benzene

Reaction equation

[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.[CH2:9](O)[C:10]#[CH:11]>>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:11][C:10]#[CH:9])=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 2879P-Cresol

HCID 7859Propargyl alcohol

Product 1

HCID 3265921-Methyl-4-(prop-2-yn-1-yloxy)benzene

Procedure

The title compound was synthesized using 4-methylphenol and propargyl alcohol by conducting a reaction similar to that mentioned in Reference example 35.

Workup

customa reaction similar to

Sources & evidence

ORD record: ord-0257165524bc4e7ba1032a0f946078a6
Source dataset: uspto-grants-2007_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07199150B2

Reaction notes

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