Pyrazole → 4-(1H-Pyrazol-1-yl)aniline
Reaction equation
Br[C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][CH:3]=1.[NH:9]1[CH:13]=[CH:12][CH:11]=[N:10]1>C(#N)C>[NH2:6][C:5]1[CH:7]=[CH:8][C:2]([N:9]2[CH:13]=[CH:12][CH:11]=[N:10]2)=[CH:3][CH:4]=1Participants
4
Reagents, catalysts & solvents 1
Procedure
General procedure B (82° C., 42 hours) was followed using 117 mg of Chxn-Py-Al (0.4 mmoles), 516 mg of 4-bromoaniline (3 mmoles), 136 mg of pyrazole (2 mmoles) and 1.2 ml of acetonitrile.
Workup
- customGeneral procedure B (82° C., 42 hours)
Sources & evidence
- ORD record
- ord-b8778862b99247fd881210292f2676d3
- Source dataset
- uspto-grants-2007_04
- Patent number
- US07202367B2
Reaction notes
Loading…