Hydrazine hydrate (1:1) → HCID 18426078, compound
Reaction equation
[CH3:1][O:2][C:3]1[CH:21]=[CH:20][C:6]([C:7]([CH:9]2[C:17](=O)[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[C:10]2=O)=O)=[CH:5][CH:4]=1.O.[NH2:23][NH2:24]>>[CH3:1][O:2][C:3]1[CH:21]=[CH:20][C:6]([C:7]2[C:9]3[CH2:17][C:16]4[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=4)[C:10]=3[NH:23][N:24]=2)=[CH:5][CH:4]=1Participants
3
Procedure
A mixture of 2-(4-methoxybenzoyl)indan-1,3-dione (1.4 g, prepared by a modification of the method disclosed in J. Het. Chem. 8, 855-859 (1971)), and hydrazine hydrate (15 ml) was boiled under reflux for 24 hours. The mixture was cooled, poured into ice-water and the solid which precipitated was collected by filtration, washed with absolute ethanol and dried to give 3-(4-methoxyphenyl)-1,4-dihydroindeno[1,2-c]pyrazole, m.p. 247° C.
Workup
- customprepared by a modification of the method
- temperatureunder reflux for 24 hours
- temperatureThe mixture was cooled
- customthe solid which precipitated
- filtration