Imidazole → Bis-(1H-imidazol-2-YL)-methanone

HRID 1282289

Reaction equation

HRID 1282289 reaction equation
[NH:1]1[CH:5]=[CH:4][N:3]=[CH:2]1.[C:6](=[O:17])(OC(Cl)(Cl)Cl)OC(Cl)(Cl)[Cl:9]>>[C:6]([C:2]1[NH:1][CH:5]=[CH:4][N:3]=1)([C:2]1[NH:1][CH:5]=[CH:4][N:3]=1)=[O:17].[ClH:9].[NH:1]1[CH:5]=[CH:4][N:3]=[CH:2]1

Participants

4

Reactant 2

HCID 795ImidazoleHCID 94429Triphosgene

Product 2

HCID 5250894Bis-(1H-imidazol-2-YL)-methanoneHCID 10197644Imidazolium chloride

Procedure

Reaction of imidazole with bis (trichloromethyl) carbonate produces carbonyl diimidazole and crystalline imidazole hydrochloride. Insoluble imidazole hydrochloride is removed from the reaction mixture quantitatively by filtration and the carbonyl diimidazole is recovered by removing the solvent or crystallization under cooling or a combination thereof.

Sources & evidence

ORD record
ord-f734730a142b45d28a7983dd411b3709
Source dataset
uspto-grants-2002_09
Patent number
US06455702B1

Linked notes

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