Triethylamine → 2-[2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethylamino]-3-methyl-4H-imidazol-5-one
Reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[O:9][C:8]([CH2:10][S:11][CH2:12][CH2:13][NH2:14])=[CH:7][CH:6]=1)[CH3:3].I.[CH3:16][N:17]1[CH2:21][C:20](=[O:22])[N:19]=[C:18]1SC.C(N(CC)CC)C>C(O)C>[CH3:3][N:2]([CH2:4][C:5]1[O:9][C:8]([CH2:10][S:11][CH2:12][CH2:13][NH:14][C:18]2[N:17]([CH3:16])[CH2:21][C:20](=[O:22])[N:19]=2)=[CH:7][CH:6]=1)[CH3:1]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
2-(5-Dimethylaminomethylfuran-2-ylmethylthio)ethylamine (2.25 g), 1-methyl-2-methylthio-imidazolin-4-one hydroiodide (2.85 g) and triethylamine (3.635 g) were refluxed in ethanol (25 ml) for 4 hours.
Sources & evidence
- ORD record
- ord-e509d6c851424fabb3fce6a44bbf29d4
- Source dataset
- uspto-grants-1986_01
- Patent number
- US04567176
Reaction notes
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