4,6-Dichloro-2-methylquinoline → 6-Chloro-2-methyl-1,2,3,4-tetrahydroquinoline
Reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([Cl:12])[CH:10]=2)[N:5]=[C:4]([CH3:13])[CH:3]=1>[Rh]>[Cl:12][C:9]1[CH:10]=[C:11]2[C:6](=[CH:7][CH:8]=1)[NH:5][CH:4]([CH3:13])[CH2:3][CH2:2]2Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
4,6-Dichloroquinaldine was reduced with rhodium on carbon to give 6-chloro-2-methyltetrahydroquinoline.
Sources & evidence
- ORD record
- ord-96cd0173c9414ec6a07db9c5d085ea95
- Source dataset
- uspto-grants-1976_10
- Patent number
- US03985882
Reaction notes
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