Benzoic Acid → 2-(2-(Benzamidomethyl)-5-carbamimidoylphenylamino)acetic acid
Reaction equation
Cl.[NH2:2][CH2:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[N:14]=C(C)O[N:11]=2)=[CH:6][C:5]=1[NH:16][CH2:17][C:18]([O:20]CC1C=CC=CC=1)=[O:19].[C:28](O)(=[O:35])[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1>>[C:28]([NH:2][CH2:3][C:4]1[CH:9]=[CH:8][C:7]([C:10](=[NH:11])[NH2:14])=[CH:6][C:5]=1[NH:16][CH2:17][C:18]([OH:20])=[O:19])(=[O:35])[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1Participants
3
Procedure
Compound 58d was reacted with benzoic acid and subsequently hydrogenated according to the the procedure described in Example 58, to give Example 62. ESI-MS m/e 327.5 (M+1).
Workup
- customto give Example 62
Sources & evidence
- ORD record
- ord-35a8daa004d34cc49b6b730574e02279