Dimethyl Sulfoxide → 2-(4-Chlorophenyl)spiro[cyclopropane-1,3'-indolin]-2'-one
Reaction equation
[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH3:4][S+:5]([CH3:6])([CH3:7])=[O:8].[CH3:9][S:10]([CH3:11])=[O:12].[Cl:13][c:14]1[cH:15][cH:16][c:17]([CH:18]=[C:19]2[C:20](=[O:28])[NH:21][c:22]3[cH:23][cH:24][cH:25][cH:26][c:27]32)[cH:29][cH:30]1.[H-:2].[I-:3].[Na+:1].[OH2:36]>>[CH2:9]1[CH:18]([c:17]2[cH:16][cH:15][c:14]([Cl:13])[cH:30][cH:29]2)[C:19]12[C:20](=[O:28])[NH:21][c:22]1[cH:23][cH:24][cH:25][cH:26][c:27]12Participants
9
Sources & evidence
- ORD record
- ord-95aad358c18548bc8674b1a11257a0b4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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