Ethanol → 1-(4-Phenyl-2-thiazolylmethyl)-4-phenylpiperazine

Reaction equation

[CH3:32][CH2:33][OH:34].[Cl:1][CH2:2][c:3]1[s:4][cH:5][c:6](-[c:8]2[cH:9][cH:10][cH:11][cH:12][cH:13]2)[n:7]1.[Na+:26].[Na+:27].[O-:28][C:29](=[O:30])[O-:31].[c:14]1([N:20]2[CH2:21][CH2:22][NH:23][CH2:24][CH2:25]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[CH2:2]([c:3]1[s:4][cH:5][c:6](-[c:8]2[cH:9][cH:10][cH:11][cH:12][cH:13]2)[n:7]1)[N:23]1[CH2:22][CH2:21][N:20]([c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[CH2:25][CH2:24]1

Participants

Reactant 5

HCID 702Ethanol

HCID 923Sodium Ion2×

HCID 70961-Phenylpiperazine

HCID 19660Carbonate Ion

HCID 225573612-(Chloromethyl)-4-phenyl-1,3-thiazole

Product 1

HCID 227625081-(4-Phenyl-2-thiazolylmethyl)-4-phenylpiperazine

Sources & evidence

ORD record: ord-079f97b489134007b5091e4a4ff00db7
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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