Dichloromethane → 2-[(4-{2-[Heptyl(5-morpholin-4-ylpyrimidin-2-yl)amino]ethyl}-1,3-thiazol-2-yl)thio]-2-methylpropionic acid

Reaction equation

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([C:7]([CH3:8])([CH3:9])[S:10][c:11]1[s:12][cH:13][c:14]([CH2:16][CH2:17][N:18]([c:19]2[n:20][cH:21][c:22]([N:25]3[CH2:26][CH2:27][O:28][CH2:29][CH2:30]3)[cH:23][n:24]2)[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37])[n:15]1)=[O:38].[Cl:46][CH2:47][Cl:48].[OH:39][C:40]([C:41]([F:42])([F:43])[F:44])=[O:45]>>[O:5]=[C:6]([C:7]([CH3:8])([CH3:9])[S:10][c:11]1[s:12][cH:13][c:14]([CH2:16][CH2:17][N:18]([c:19]2[n:20][cH:21][c:22]([N:25]3[CH2:26][CH2:27][O:28][CH2:29][CH2:30]3)[cH:23][n:24]2)[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37])[n:15]1)[OH:38]