Dichloromethane → 5-{3-[4-(3,4-Difluoro-phenyl)-6-trifluoromethyl-pyrimidin-2-yl]-phenyl}-thiophene-2-sulfonic acid amide

Reaction equation

[C:1]([CH3:2])([CH3:3])([CH3:4])[NH:5][S:6](=[O:7])(=[O:8])[c:9]1[s:10][c:11](-[c:14]2[cH:15][c:16](-[c:20]3[n:21][c:22](-[c:30]4[cH:31][c:32]([F:37])[c:33]([F:36])[cH:34][cH:35]4)[cH:23][c:24]([C:26]([F:27])([F:28])[F:29])[n:25]3)[cH:17][cH:18][cH:19]2)[cH:12][cH:13]1.[Cl:45][CH2:46][Cl:47].[F:38][C:39]([F:40])([F:41])[C:42]([OH:43])=[O:44]>>[NH2:5][S:6](=[O:7])(=[O:8])[c:9]1[s:10][c:11](-[c:14]2[cH:15][c:16](-[c:20]3[n:21][c:22](-[c:30]4[cH:31][c:32]([F:37])[c:33]([F:36])[cH:34][cH:35]4)[cH:23][c:24]([C:26]([F:27])([F:28])[F:29])[n:25]3)[cH:17][cH:18][cH:19]2)[cH:12][cH:13]1