Hydrochloric Acid → ethyl 3-amino-3-(3-methoxyphenyl)propanoate hydrochloride
Reaction equation
[NH2:1][CH:2]([C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([O:13][CH3:14])[CH:8]=1)[CH2:3][C:4]([OH:6])=[O:5].[ClH:15].[CH2:16](O)[CH3:17]>>[ClH:15].[NH2:1][CH:2]([C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([O:13][CH3:14])[CH:8]=1)[CH2:3][C:4]([O:6][CH2:16][CH3:17])=[O:5]Participants
4
Procedure
Corresponding to Example 1b, 60 g of (8a) were treated with hydrochloric acid in ethanol. A white, crystalline product was obtained (yield: 75 g).
Workup
- customA white, crystalline product was obtained (yield: 75 g)
Sources & evidence
- ORD record
- ord-bd06617ff20049428e27e4576cc6c420
- Source dataset
- uspto-grants-2003_07
- Patent number
- US06589972B2
Reaction notes
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