Ammonium Hydroxide → HCID 18506197, compound

Reaction equation

[NH2:1][C:2]1[CH:19]=[CH:18][CH:17]=[CH:16][C:3]=1[O:4][C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][CH:13]=1)[C:10](=[O:14])[NH:9][C:8]2=[O:15].[OH-].[NH4+:21]>>[NH2:1][C:2]1[CH:19]=[CH:18][CH:17]=[CH:16][C:3]=1[O:4][C:5]1[CH:6]=[C:7]([C:8]([NH2:21])=[O:15])[C:11](=[CH:12][CH:13]=1)[C:10]([NH2:9])=[O:14]

Participants

Reactant 2

HCID 14923Ammonium Hydroxide

HCID 18506076HCID 18506076, compound

Product 1

HCID 18506197HCID 18506197, compound

Procedure

5-(2-Aminophenoxy)-isoindole-1,3-dione (0.1 g, 0.38 mmol) in conc. ammonium hydroxide (aq) was stirred at 60° C. for two hours. The reaction mixture was evaporated in vacuo (cold in order not to make the imide again). The crude mixture was used without any purification.

Workup

customThe reaction mixture was evaporated in vacuo (cold in order not
customThe crude mixture was used without any purification

Sources & evidence

ORD record: ord-fc642962978f4fe8bbdcf534f802d180
Source dataset: uspto-grants-2003_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06590118B1

Reaction notes

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