2-Aminopyridine → 2-Ethylimidazo[1,2-a]pyridine

Reaction equation

[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][N:3]=1.Br[CH2:9][C:10](=O)[CH2:11][CH3:12]>>[CH2:11]([C:10]1[N:1]=[C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][N:3]2[CH:9]=1)[CH3:12]

Participants

Reactant 2

HCID 104392-Aminopyridine

HCID 131561-Bromo-2-butanone

Product 1

HCID 218319912-Ethylimidazo[1,2-a]pyridine

Procedure

The title compound was prepared from 2-aminopyridine and 1-bromo-2-butanone, employing procedures analogous to those described in Procedure 27 Step A.

Sources & evidence

ORD record: ord-e8b9639103724f63a8ccdf6cb7ff8a11
Source dataset: uspto-grants-2003_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06593346B2

Reaction notes

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