2,2-Diphenylacetyl chloride → N-[1,3,4]Oxadiazol-2-yl-2,2-diphenyl-acetamide

HRID 1358429

Reaction equation

HRID 1358429 reaction equation
[O:1]1[CH:5]=[N:4][N:3]=[C:2]1[NH2:6].[C:7]1([CH:13]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[C:14](Cl)=[O:15])[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>>[O:1]1[CH:5]=[N:4][N:3]=[C:2]1[NH:6][C:14](=[O:15])[CH:13]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 746372,2-Diphenylacetyl chlorideHCID 2397872-Amino-1,3,4-oxadiazole

Product 1

HCID 22661051N-[1,3,4]Oxadiazol-2-yl-2,2-diphenyl-acetamide

Procedure

The title compound, light yellow solid, m.p. 131-132° C. and MS: m/e=279.2 (M+) was prepared in accordance with the general method of example 44a from [1,3,4]oxadiazol-2-ylamine and 2,2-diphenylacetic acid chloride.

Sources & evidence

ORD record
ord-394a79a402fa475293f26e57c00517a0
Source dataset
uspto-grants-2003_07
Patent number
US06596743B2

Linked notes

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