Hydrochloric Acid → 4-(3-Cyano-6,7-dimethoxy-quinolin-4-ylamino)-benzamide

HRID 135844

Reaction equation

HRID 135844 reaction equation
[CH3:35][CH2:36][O:37][CH2:38][CH2:39][OH:40].[Cl:1][c:2]1[c:3]([C:16]#[N:17])[cH:4][n:5][c:6]2[cH:7][c:8]([O:14][CH3:15])[c:9]([O:12][CH3:13])[cH:10][c:11]12.[ClH:18].[NH2:25][c:26]1[cH:27][cH:28][c:29]([C:30](=[O:31])[NH2:32])[cH:33][cH:34]1.[n:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1>>[c:2]1([NH:25][c:26]2[cH:27][cH:28][c:29]([C:30](=[O:31])[NH2:32])[cH:33][cH:34]2)[c:3]([C:16]#[N:17])[cH:4][n:5][c:6]2[cH:7][c:8]([O:14][CH3:15])[c:9]([O:12][CH3:13])[cH:10][c:11]12

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 1049PyridineHCID 8076Glycol monoethyl etherHCID 760794-AminobenzamideHCID 105866764-Chloro-6,7-dimethoxy-quinoline-3-carbonitrile

Product 1

HCID 224667654-(3-Cyano-6,7-dimethoxy-quinolin-4-ylamino)-benzamide

Sources & evidence

ORD record
ord-7adf3d56a58d45d0a0880228131e9d31
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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