Hydrogen Bromide → HCID 178515992, compound

HRID 1359265Notes

Reaction equation

HRID 1359265 reaction equation
[CH2:1]([C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([O:14]C)[N:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Br>O>[CH2:1]([C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([OH:14])[N:9]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 260Hydrogen BromideHCID 219422742-Benzyl-6-methoxypyridine

Product 1

HCID 178515992HCID 178515992, compoundYield 70.9%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 59 g of 2-benzyl-6-methoxypyridine and 200 ml of 47% hydrobromic acid was heated under stirring for 7 hours in an oil bath kept at 100° C. After cooling as it was, 250 ml of water was added thereto, and the resulting crystals were collected by filtration, washed with water and vacuum-dried, to give 38.9 g of the target compound.

Workup

  1. temperaturewas heated
  2. customkept at 100° C
  3. temperatureAfter cooling as it
  4. filtrationthe resulting crystals were collected by filtration
  5. washwashed with water
  6. customvacuum-dried

Sources & evidence

ORD record
ord-05486037a3b44e6cb1ec2598db258d0c
Source dataset
uspto-grants-2003_07
Patent number
US06599917B1

Reaction notes

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