1-(4-Methylpiperazino)-3-[2-(octadecyloxy)phenyl]-1-propanone → HCID 18520285, compound
Reaction equation
[ClH:1].C(OCC)(=O)C.[CH3:8][N:9]1[CH2:14][CH2:13][N:12]([C:15](=[O:43])[CH2:16][CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=2[O:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42])[CH2:11][CH2:10]1>C(OCC)(=O)C>[ClH:1].[CH3:8][N:9]1[CH2:10][CH2:11][N:12]([C:15](=[O:43])[CH2:16][CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=2[O:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42])[CH2:13][CH2:14]1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
4N Hydrochloric acid/ethyl acetate solution (0.24 ml) was added to a solution containing 1-(4-methylpiperazino)-3-[2-(octadecyloxy)phenyl]-1-propanone (0.38 g) in ethyl acetate (4 ml) at room temperature. After being stirred for 15 minutes, the reaction mixture was concentrated. The residue was recrystallized with the mixed solution of ethyl acetate-ethanol, thereby yielding the entitled compound (0.38 g) as white solid.