HCID 178419650, compound → HCID 178487489, compound

HRID 1368520

Reaction equation

HRID 1368520 reaction equation
[NH:1]1[CH:5]=[C:4]([C:6]([C:8]2[CH:17]=[CH:16][C:15]3[C:10](=[CH:11][CH:12]=[C:13]([O:18][CH3:19])[CH:14]=3)[CH:9]=2)=[O:7])[N:3]=[CH:2]1.[CH:20]1([Mg]Br)[CH2:24][CH2:23][CH2:22][CH2:21]1>C1COCC1>[CH:20]1([C:6]([C:4]2[N:3]=[CH:2][NH:1][CH:5]=2)([C:8]2[CH:17]=[CH:16][C:15]3[C:10](=[CH:11][CH:12]=[C:13]([O:18][CH3:19])[CH:14]=3)[CH:9]=2)[OH:7])[CH2:24][CH2:23][CH2:22][CH2:21]1

Participants

4

Reactant 2

HCID 178419650HCID 178419650, compoundHCID 178487490HCID 178487490, compound

Product 1

HCID 178487489HCID 178487489, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

In a similar manner to that described in Example 1-(iv), the reaction of (1H-imidazol-4-yl)-(6-methoxynaphthalen-2-yl)ketone (0.60 g) with cyclopentylmagnesium bromide in THF (1.0 M, 10 ml) was carried out to give the titled compound (0.80 g) as a colorless solid.

Sources & evidence

ORD record
ord-c2b20b9f3d5a4e7789975709a6c15b2c
Source dataset
uspto-grants-2003_06
Patent number
US06573289B1

Linked notes

Loading…