Acetone → 1-tert-Butyl 2-methyl 4-oxopyrrolidine-1,2-dicarboxylate

Reaction equation

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:14](=[O:15])[O:16][CH3:17])[CH2:10][CH:11]([OH:13])[CH2:12]1.[CH3:18][C:19](=[O:20])[CH3:21].[CH:32]([OH:33])([CH3:34])[CH3:35].[O:22]=[Cr:23](=[O:24])=[O:25].[OH2:26].[S:27](=[O:28])(=[O:29])([OH:30])[OH:31]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:14](=[O:15])[O:16][CH3:17])[CH2:10][C:11](=[O:13])[CH2:12]1

Participants

Reactant 6

HCID 180Acetone

HCID 962Water

HCID 1118Sulfuric Acid

HCID 3776Isopropanol

HCID 14915Chromium Trioxide

HCID 51482991-Tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate

Product 1

HCID 42518531-tert-Butyl 2-methyl 4-oxopyrrolidine-1,2-dicarboxylate

Sources & evidence

ORD record: ord-01fa1077efec496c89eaa1c3ba2b2832
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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