Chloride → 1-(2-Phenoxy-2-methylpropionyl)-4-(4 methoxybenzyl)piperazine

HRID 1378331

Reaction equation

HRID 1378331 reaction equation
[Cl-].[O:2]([C:9]([CH3:14])([CH3:13])[C:10]([OH:12])=O)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[CH3:15][O:16][C:17]1[CH:29]=[CH:28][C:20]([CH2:21][N:22]2[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]2)=[CH:19][CH:18]=1>>[O:2]([C:9]([CH3:14])([CH3:13])[C:10]([N:25]1[CH2:24][CH2:23][N:22]([CH2:21][C:20]2[CH:28]=[CH:29][C:17]([O:16][CH3:15])=[CH:18][CH:19]=2)[CH2:27][CH2:26]1)=[O:12])[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1

Participants

4

Reactant 3

HCID 312ChlorideHCID 70343Fibric acidHCID 2319051-((4-Methoxyphenyl)methyl)piperazine

Product 1

HCID 214722211-(2-Phenoxy-2-methylpropionyl)-4-(4 methoxybenzyl)piperazine

Procedure

By carrying out the preparation as in Example 12, but using the chloride of 2-phenoxy-2-methylpropionic acid and 1-(4-methoxybenzyl)piperazine, the title product is obtained.

Workup

  1. customthe preparation as in Example 12

Sources & evidence

ORD record
ord-3ce3921afa964d8190cfa2dfadd6aa17
Source dataset
uspto-grants-1997_09
Patent number
US05668138

Linked notes

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