HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imatinib amine → 4-(1-methylpiperidin-4-yloxy)-3-trifluoromethyl-N-{4-methyl-3-[4-(3-pyridyl)pyrimidin-2-ylamino]phenyl}benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imatinib amine | HCID 9965429 | — |
| Reactant | 4-(1-Methylpiperidin-4-yloxy)-3-trifluoromethylbenzoyl chloride hydrochloride | HCID 23145894 | — |
| Product | 4-(1-methylpiperidin-4-yloxy)-3-trifluoromethyl-N-{4-methyl-3-[4-(3-pyridyl)pyrimidin-2-ylamino]phenyl}benzamide | HCID 11376424 | — |
Reaction Steps
This compound was prepared in the same manner as in Example 1, except that 4-methyl-3-[4-(3-pyridyl)pyrimidin-2-ylamino]aniline (Patent Document 1) and 4-(1-methylpiperidin-4-yloxy)-3-trifluoromethylbenzoyl chloride hydrochloride (Reference Example 11) were used.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07728131B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-abef090c3a5a45098ce3938ea325d5ea |
| Source note | uspto-grants-2010_06 |