Ethanesulfonyl chloride → 3-Methoxy-4-(7H-purin-8-yl)phenyl ethanesulfonate

Reaction equation

[CH3:1][O:2][C:3]1[CH:8]=[C:7]([OH:9])[CH:6]=[CH:5][C:4]=1[C:10]1[NH:18][C:17]2[C:12](=[N:13][CH:14]=[N:15][CH:16]=2)[N:11]=1.[CH2:19]([S:21](Cl)(=[O:23])=[O:22])[CH3:20]>>[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][S:21]([CH2:19][CH3:20])(=[O:23])=[O:22])[CH:6]=[CH:5][C:4]=1[C:10]1[NH:18][C:17]2[C:12](=[N:13][CH:14]=[N:15][CH:16]=2)[N:11]=1

Participants

Reactant 2

HCID 11667Ethanesulfonyl chloride

HCID 1360676254-(7,9-Dihydro-8H-purin-8-ylidene)-3-methoxycyclohexa-2,5-dien-1-one

Product 1

HCID 132845173-Methoxy-4-(7H-purin-8-yl)phenyl ethanesulfonate

Procedure

Prepared analogously to Example 1 from 8-(2'-methoxy-4'-hydroxy-phenyl)-purine and ethanesulfonic acid chloride.

Sources & evidence

ORD record: ord-b0e56de9b4ae425ab05352dec2c5337a
Source dataset: uspto-grants-1986_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04582837

Reaction notes

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