Trifluoroacetic acid → HCID 18319061, compound

Reaction equation

CC([O:5][C:6](=[O:23])[CH2:7][O:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][CH2:16][C:17](=[O:22])[C:18]([F:21])([F:20])[F:19])=[CH:11][CH:10]=1)(C)C.FC(F)(F)C(O)=O>>[F:19][C:18]([F:20])([F:21])[C:17](=[O:22])[CH2:16][CH2:15][C:12]1[CH:13]=[CH:14][C:9]([O:8][CH2:7][C:6]([OH:23])=[O:5])=[CH:10][CH:11]=1

Participants

Reactant 2

HCID 6422Trifluoroacetic acid

HCID 57301381HCID 57301381, compound

Product 1

HCID 18319061HCID 18319061, compoundYield 100%

Procedure

4-(4,4,4-trifluoro-3-oxo-1-butyl)phenoxyacetic acid 1,1-dimethylethyl ester (0.450 g, 1.35 mmol) was treated with trifluoroacetic acid as described in example (133) to give 0.373 g (100%) of the material as a white solid.

Sources & evidence

ORD record: ord-c726bbcbf4234d51af78f54fcedf2f05
Source dataset: uspto-grants-2001_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06255496B1

Reaction notes

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