Hydrogen Bromide → [2-(2-Thienyl)ethylamino](2-chlorophenyl)acetamide hydrobromide
Reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][CH2:7][NH:8][CH:9]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[Cl:19])[C:10]([NH2:12])=[O:11].[BrH:20]>CC(C)=O>[BrH:20].[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][CH2:7][NH:8][CH:9]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[Cl:19])[C:10]([NH2:12])=[O:11]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
14.7 g (0.05 mol) of [2-(2-thienyl)ethylamino](2-chlorophenyl)acetamide, prepared as described in Example 7, is dissolve din 150 ml of acetone. To the solution 4 ml of 60% aqueous hydrogen bromide solution is added and the precipitated white crystals are filtered off, washed with acetone and dried.