Dimethylamine → N'-{4-[1-ethyl-4-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl]phenyl}N,N-dimethylurea

Reaction equation

[CH2:1]([CH3:2])[n:3]1[n:4][c:5](-[c:18]2[cH:19][cH:20][c:21]([NH2:22])[cH:23][cH:24]2)[c:6](-[c:8]2[c:9]3[c:10]([n:11][cH:12][c:13]2[F:14])[nH:15][cH:16][cH:17]3)[cH:7]1.[CH3:25][NH:26][CH3:27].[O:28]1[CH2:31][CH2:30][CH2:29][CH2:32]1>>[CH2:1]([CH3:2])[n:3]1[n:4][c:5](-[c:18]2[cH:19][cH:20][c:21]([NH:22][C:32]([N:26]([CH3:25])[CH3:27])=[O:28])[cH:23][cH:24]2)[c:6](-[c:8]2[c:9]3[c:10]([n:11][cH:12][c:13]2[F:14])[nH:15][cH:16][cH:17]3)[cH:7]1

Participants

Reactant 3

HCID 674Dimethylamine

HCID 8028Tetrahydrofuran

HCID 690026924-[1-ethyl-4-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl]aniline

Product 1

HCID 58980039N'-{4-[1-ethyl-4-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl]phenyl}N,N-dimethylurea

Sources & evidence

ORD record: ord-b57803c2547248d0b26064d232c0d41d
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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