tert-Butyldimethylsilyl chloride → 4-(t-Butyldimethylsilanyloxy)-2-fluoro-5-methoxybenzaldehyde

HRID 138961

Reaction equation

HRID 138961 reaction equation
[C:13]([CH3:14])([CH3:15])([CH3:16])[Si:17]([CH3:18])([CH3:19])[Cl:20].[Cl:32][Si:33]([CH:34]([CH3:35])[CH3:36])([CH:37]([CH3:38])[CH3:39])[CH:40]([CH3:41])[CH3:42].[F:1][c:2]1[c:3]([CH:4]=[O:5])[cH:6][c:7]([O:11][CH3:12])[c:8]([OH:10])[cH:9]1.[OH:21][c:22]1[cH:23][c:24]([CH:30]=[O:31])[cH:25][c:26]([O:27][CH3:28])[cH:29]1>>[F:1][c:2]1[c:3]([CH:4]=[O:5])[cH:6][c:7]([O:11][CH3:12])[c:8]([O:10][Si:17]([C:13]([CH3:14])([CH3:15])[CH3:16])([CH3:18])[CH3:19])[cH:9]1

Participants

5

Reactant 4

HCID 28928tert-Butyldimethylsilyl chlorideHCID 139400Triisopropylsilyl chlorideHCID 5981552-Fluoro-4-hydroxy-5-methoxybenzaldehydeHCID 53145613-Hydroxy-5-methoxybenzaldehyde

Product 1

HCID 595171104-(t-Butyldimethylsilanyloxy)-2-fluoro-5-methoxybenzaldehyde

Sources & evidence

ORD record
ord-2090f5e454134cda9b353e7c9b453241
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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