Ethanol → HCID 178524964, compound
Reaction equation
[Na:1].C(O)C.[NH2:5][C:6]1[S:10][N:9]=[N:8][C:7]=1[C:11]([O:13]CC)=[O:12]>O>[Na:1].[Na:1].[Na:1].[C:11]([C:7]1[N:8]=[N:9][NH:5][C:6]=1[SH:10])([OH:13])=[O:12]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
To a solution of 4.6 g. (0.20 mol.) of sodium and 250 ml. of absolute ethanol was added under a nitrogen atmosphere 8.65 g. (0.05 mol.) of 5-amino-4-carbethoxy-1,2,3-thiadiazole. The reaction mixture was stirred one hour, 5 ml. of water was added and the mixture was refluxed for 12 hours. After cooling, the mixture was filtered and the solid product was washed with ethanol and ether and dried to give 4-carboxy-1,2,3-triazole-5-thiol trisodium salt.
Workup
- temperaturethe mixture was refluxed for 12 hours
- temperatureAfter cooling
- filtrationthe mixture was filtered
- washthe solid product was washed with ethanol and ether
- customdried
Sources & evidence
- ORD record
- ord-061e80b6095f4169b475e1915eae373f
- Source dataset
- uspto-grants-1979_02
- Patent number
- US04142046
Reaction notes
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