Phosgene → 6-[p-(m-chlorobenzyloxycarbonylamino)-phenyl]-4,5-dihydro-5-methyl-3(2H)-pyridazinone

HRID 139669

Reaction equation

HRID 139669 reaction equation
[Cl:10][C:11]([Cl:12])=[O:13].[Cl:1][c:2]1[cH:3][c:4]([CH2:5][OH:6])[cH:7][cH:8][cH:9]1.[NH2:14][c:15]1[cH:16][cH:17][c:18]([C:21]2=[N:26][NH:25][C:24](=[O:27])[CH2:23][CH:22]2[CH3:28])[cH:19][cH:20]1.[O:29]1[CH2:30][CH2:31][CH2:32][CH2:33]1>>[Cl:1][c:2]1[cH:3][c:4]([CH2:5][O:6][C:11](=[O:13])[NH:14][c:15]2[cH:16][cH:17][c:18]([C:21]3=[N:26][NH:25][C:24](=[O:27])[CH2:23][CH:22]3[CH3:28])[cH:19][cH:20]2)[cH:7][cH:8][cH:9]1

Participants

5

Reactant 4

HCID 6371PhosgeneHCID 8028TetrahydrofuranHCID 701173-Chlorobenzyl alcoholHCID 161928Ici 109,081

Product 1

HCID 128050426-[p-(m-chlorobenzyloxycarbonylamino)-phenyl]-4,5-dihydro-5-methyl-3(2H)-pyridazinone

Sources & evidence

ORD record
ord-63505de12fbe443684552720f9d34b0f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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