Reaction equation
[OH-:1].[Na+:2].[C:3]([OH:12])(=[O:11])[C@@H:4]([C@H:6]([C:8]([OH:10])=[O:9])[OH:7])[OH:5]>O>[C:8]([C@@H:6]([C@H:4]([C:3]([O-:12])=[O:11])[OH:5])[OH:7])([O-:10])=[O:9].[Na+:2].[Na+:2].[OH-:1].[Na+:2]Participants
5
Reactant 2
Product 2
Reagents, catalysts & solvents 1
Procedure
In a 1-liter reactor vessel, 606.04 g of NaOH solution (containing 50 wt % of NaOH and 50 wt % of water) were mixed with 414.40 g water and 96.70 g of L-tartaric acid. Upon mixing, a mixture comprising 11.2 wt % of disodium L-tartrate, 22.5 wt % of NaOH, and 66.3 wt % of water was obtained. The mixture was heated and was kept at atmospheric boiling conditions under reflux for 26 hours (Tboil˜110° C.), under continuous stirring. A clear solution was obtained. At regular intervals, a sample was taken from the liquid and analyzed by 1H-NMR for meso-tartaric acid, DL-tartaric acid, and acetate content (a distinction between the D and L-enantiomer cannot be made by 1H-NMR).
Workup
- additionUpon mixing
Sources & evidence
- ORD record
- ord-c80706f20a6c49e998bf6795bcd6f788
- Source dataset
- uspto-grants-2014_12
- Patent number
- US08911796B2
Linked notes
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