Acetophenone → 3-(4-Bromophenyl)-1-phenylprop-2-en-1-one

Reaction equation

[Br:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=O)=[CH:4][CH:3]=1.[C:10]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)(=[O:12])[CH3:11]>>[Br:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[CH:11][C:10]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[O:12])=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 7410Acetophenone

HCID 707414-Bromobenzaldehyde

Product 1

HCID 1021593-(4-Bromophenyl)-1-phenylprop-2-en-1-one

Procedure

By a procedure similar to that of example 1.59.1, starting from 4-bromobenzaldehyde and acetophenone, 3-(4-bromophenyl)-1-phenylprop-2-en-1-one was obtained as yellow solid.

Sources & evidence

ORD record: ord-ecd882c6c5ae4bb8a51017558c42d6a7
Source dataset: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08912186B2

Reaction notes

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