Methanol → (+/-)2-Methyl-1-phenyl-2-(1-piperidinyl)-1-propanamine

HRID 140546

Reaction equation

HRID 140546 reaction equation
[BH4-:19].[CH2:37]([O:38][CH2:39][CH2:40][CH2:41][CH3:42])[CH2:43][CH2:44][CH3:45].[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[CH3:1][C:2]([C:3]#[N:4])([CH3:5])[N:6]1[CH2:7][CH2:8][CH2:9][CH2:10][CH2:11]1.[CH3:51][OH:52].[Li:12][c:13]1[cH:14][cH:15][cH:16][cH:17][cH:18]1.[NH2:21][CH:22]([c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1)[C:29]1([N:30]([CH3:31])[CH3:32])[CH2:33][CH2:34][CH2:35][CH2:36]1.[Na+:20]>>[CH3:1][C:2]([CH:3]([NH2:4])[c:13]1[cH:14][cH:15][cH:16][cH:17][cH:18]1)([CH3:5])[N:6]1[CH2:7][CH2:8][CH2:9][CH2:10][CH2:11]1

Participants

9

Reactant 8

HCID 887MethanolHCID 923Sodium ionHCID 8028TetrahydrofuranHCID 8909Butyl etherHCID 28123BorohydrideHCID 2888822-Methyl-2-piperidin-1-ylpropanenitrileHCID 11521393{1-[Amino(phenyl)methyl]cyclopentyl}dimethylamineHCID 178506676HCID 178506676, compound

Product 1

HCID 199304(+/-)2-Methyl-1-phenyl-2-(1-piperidinyl)-1-propanamine

Sources & evidence

ORD record
ord-43d4674e1a8b493ca02a954e40de7576
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

Loading…