Hydrochloric Acid → 4-Amino-2-fluoro-5-nitrobenzoic acid
Reaction equation
C([NH:4][C:5]1[C:13]([N+:14]([O-:16])=[O:15])=[CH:12][C:8]([C:9]([OH:11])=[O:10])=[C:7]([F:17])[CH:6]=1)(=O)C.Cl>O1CCOCC1>[NH2:4][C:5]1[C:13]([N+:14]([O-:16])=[O:15])=[CH:12][C:8]([C:9]([OH:11])=[O:10])=[C:7]([F:17])[CH:6]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
Prepared analogously to example 145b from 4-acetylamino-2-fluoro-5-nitro-benzoic acid and half-conc. hydrochloric acid in dioxane.
Sources & evidence
- ORD record
- ord-3b58e9717b744d12acc4f82c63d1455c
- Source dataset
- uspto-grants-2014_12
- Patent number
- US08916599B2
Reaction notes
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