Thionyl Chloride → 4-Amino-5-nitro-2-fluoro-benzoyl chloride
Reaction equation
[NH2:1][C:2]1[C:10]([N+:11]([O-:13])=[O:12])=[CH:9][C:5]([C:6](O)=[O:7])=[C:4]([F:14])[CH:3]=1.S(Cl)([Cl:17])=O>ClCCCl>[NH2:1][C:2]1[C:10]([N+:11]([O-:13])=[O:12])=[CH:9][C:5]([C:6]([Cl:17])=[O:7])=[C:4]([F:14])[CH:3]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
Prepared analogously to example 53a from 4-amino-5-nitro-2-fluoro-benzoic acid and thionyl chloride in 1,2-dichloroethane.
Sources & evidence
- ORD record
- ord-dce61302b2cc40dfb349ecacfd1c3a60
- Source dataset
- uspto-grants-2014_12
- Patent number
- US08916599B2
Reaction notes
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