Tetrahydrofuran → HCID 67230022, compound
Reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([CH:17]=[CH:18][C:19]=1[NH:20][CH3:21])[C:7]([NH:9][C:10]1[CH:15]=[CH:14][C:13]([Br:16])=[CH:12][CH:11]=1)=[O:8])([O-])=O.C1COCC1>CO>[NH2:1][C:4]1[CH:5]=[C:6]([CH:17]=[CH:18][C:19]=1[NH:20][CH3:21])[C:7]([NH:9][C:10]1[CH:11]=[CH:12][C:13]([Br:16])=[CH:14][CH:15]=1)=[O:8]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A mixture of 3-Nitro-N-(4-bromophenyl)-4-methylaminobenzamide (120 mg, 0.34 mmol), 10 ml THF, 10 ml MeOH and 30 mg 5%-Pt-on-carbon was stirred for 4 h under a hydrogen atmosphere (3.5 bar). The catalyst was removed by filtration and the mixture was concentrated and used in the next step without further purification.
Workup
- customThe catalyst was removed by filtration