Acetone → 6-Methylhepta-3,5-dien-2-one
Reaction equation
[CH3:1][C:2]([CH3:6])=[CH:3][CH:4]=O.[CH3:7][C:8]([CH3:10])=[O:9]>[O-2].[Zn+2]>[CH3:1][C:2](=[CH:3][CH:4]=[CH:7][C:8](=[O:9])[CH3:10])[CH3:6]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 180 °C
Procedure
A mixture of 50 parts of 3,3-dimethylacrolein, 100 parts of acetone and 12 parts of zinc oxide is heated for 3 hours at 180° C and a pressure of 45 atmosphere in a vibrated autoclave. The reactor is then cooled and the mixture is fractionally distilled. 52.5 parts of 2-methyl-2,4-heptadien-6-one is obtained in a yield of 93% of theory based on 3,3-dimethylacrolein at a conversion 76% of theory and with a boiling point of 92° C at 15 mm Hg.
Workup
- temperatureThe reactor is then cooled
- distillationthe mixture is fractionally distilled
Sources & evidence
- ORD record
- ord-9bade372e3a34e03b1da0aa1d20b767b
- Source dataset
- uspto-grants-1977_01
- Patent number
- US04005147
Reaction notes
Loading…