Trimethylsilyl cyanide → alpha-(4-Chlorophenyl)-alpha-(4-methylthioanilino)acetonitrile

HRID 1415749

Reaction equation

[Cl:1][C:2]1[CH:17]=[CH:16][C:5]([CH:6]=[N:7][C:8]2[CH:13]=[CH:12][C:11]([S:14][CH3:15])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.C[Si]([C:22]#[N:23])(C)C>>[Cl:1][C:2]1[CH:17]=[CH:16][C:5]([CH:6]([NH:7][C:8]2[CH:13]=[CH:12][C:11]([S:14][CH3:15])=[CH:10][CH:9]=2)[C:22]#[N:23])=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 82115Trimethylsilyl cyanide

HCID 21862850N-(4-Chlorobenzylidene)-4-methylthioaniline

Product 1

HCID 21862778alpha-(4-Chlorophenyl)-alpha-(4-methylthioanilino)acetonitrile

Procedure

Following a procedure similar to that described in Example 1(ii), but using N-(4-chlorobenzylidene)-4-methylthioaniline [prepared as described in step (i) above] and trimethylsilyl cyanide as starting materials, the title compound was obtained as a pale yellow powder (yield 84%).

Sources & evidence

ORD record: ord-2e9f2f90c0854982aeddef6faa5ef0ca
Source dataset: uspto-grants-1999_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05908858

Linked notes

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